Causes
We do not yet know what causes schizophrenia. There are many theories, but it is most likely a result of genetic factors that trigger complex changes in the brain's chemistry and structure. Research has demonstrated that people with schizophrenia have changes in brain function and anatomy. However, it's not clear whether schizophrenia is a single disorder or a number of "syndromes" with different causes.
Some experts believe that the condition is triggered by stressors (e.g., substance misuse, stressful life events) in people whose brains are predisposed.